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Structure paper

TitleMolecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page E4036-E4045, Year 2015
Publish dateJun 9, 2015 (structure data deposition date)
AuthorsSekiyama, N. / Arthanari, H. / Papadopoulos, E. / Rodriguez-Mias, R.A. / Wagner, G. / Leger-Abraham, M.
External linksProc. Natl. Acad. Sci. USA / PubMed:26170285
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-5bxv:
eIF4E complex
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-MGP:
7-METHYL-GUANOSINE-5'-TRIPHOSPHATE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsTRANSLATION / Complex

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