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-Structure paper
Title | Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 25, Page 4824-4827, Year 2015 |
Publish date | Jun 15, 2015 (structure data deposition date) |
![]() | Lee, W.G. / Frey, K.M. / Gallardo-Macias, R. / Spasov, K.A. / Chan, A.H. / Anderson, K.S. / Jorgensen, W.L. |
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Methods | X-ray diffraction |
Resolution | 2.6 - 2.841 Å |
Structure data | ![]() PDB-5c24: ![]() PDB-5c25: |
Chemicals | ![]() ChemComp-4XO: ![]() ChemComp-MG: ![]() ChemComp-SO4: ![]() ChemComp-HOH: ![]() ChemComp-639: |
Source |
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![]() | TRANSFERASE / HYDROLASE/INHIBITOR / HIV / reverse transcriptase / non-nucleoside inhibitor / indolizine / triazine / polymerase / HYDROLASE-INHIBITOR complex / HYDROLASE-DNA-INHIBITOR complex |