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TitleA Crystallin Fold in the Interleukin-4-Inducing Principle of Schistosoma Mansoni Eggs (Ipse/Alpha-1) Mediates Ige Binding for Antigen-Independent Basophil Activation
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 22111-, Year 2015
Publish dateFeb 22, 2012 (structure data deposition date)
AuthorsMeyer, N.H. / Mayerhofer, H. / Tripsianes, K. / Blindow, S. / Barths, D. / Mewes, A. / Weimar, T. / Kohli, T. / Bade, S. / Madl, T. ...Meyer, N.H. / Mayerhofer, H. / Tripsianes, K. / Blindow, S. / Barths, D. / Mewes, A. / Weimar, T. / Kohli, T. / Bade, S. / Madl, T. / Frey, A. / Haas, H. / Mueller-Dieckmann, J. / Sattler, M. / Schramm, G.
External linksJ. Biol. Chem. / PubMed:26163514
MethodsNMR (solution) / X-ray diffraction
Resolution1.71 Å
Structure data

PDB-4aka:
IPSE alpha-1, an IgE-binding crystallin
Method: SOLUTION NMR

PDB-4el6:
Crystal structure of IPSE/alpha-1 from Schistosoma mansoni eggs
Method: X-RAY DIFFRACTION / Resolution: 1.71 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • schistosoma mansoni (invertebrata)
KeywordsIMMUNE SYSTEM / SCHISTOSOMA MANSONI / IMMUNOGLOBULIN BINDING / SIGNALING PROTEIN / beta/gamma-crystallin superfamily / Triggers IL4 release / IgE

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