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Structure paper

TitleCrystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction.
Journal, issue, pagesCell Death Dis, Vol. 6, Page e1809-e1809, Year 2015
Publish dateApr 28, 2015 (structure data deposition date)
AuthorsRobin, A.Y. / Krishna Kumar, K. / Westphal, D. / Wardak, A.Z. / Thompson, G.V. / Dewson, G. / Colman, P.M. / Czabotar, P.E.
External linksCell Death Dis / PubMed:26158515
MethodsX-ray diffraction
Resolution1.797 - 2.5 Å
Structure data

PDB-4zie:
Crystal Structure of core/latch dimer of Bax in complex with BimBH3
Method: X-RAY DIFFRACTION / Resolution: 1.797 Å

PDB-4zif:
Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini
Method: X-RAY DIFFRACTION / Resolution: 2.401 Å

PDB-4zig:
Crystal Structure of core/latch dimer of Bax in complex with BidBH3mini
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-4zih:
Crystal Structure of core/latch dimer of Bax in complex with BimBH3mini
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-4zii:
Crystal Structure of core/latch dimer of BaxI66A in complex with BidBH3
Method: X-RAY DIFFRACTION / Resolution: 2.191 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / Bax / BH3 domain / Structural Genomics / The Walter and Eliza Hall Institute of Medical Research

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