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Structure paper

TitleStructure of LacY with an alpha-substituted galactoside: Connecting the binding site to the protonation site.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 9004-9009, Year 2015
Publish dateMay 22, 2015 (structure data deposition date)
AuthorsKumar, H. / Finer-Moore, J.S. / Kaback, H.R. / Stroud, R.M.
External linksProc. Natl. Acad. Sci. USA / PubMed:26157133
MethodsX-ray diffraction
Resolution3.312 Å
Structure data

PDB-4zyr:
Crystal structure of E. coli Lactose permease G46W/G262W bound to p-nitrophenyl alpha-D-galactopyranoside (alpha-NPG)
Method: X-RAY DIFFRACTION / Resolution: 3.312 Å

Chemicals

ChemComp-9PG:
4-nitrophenyl alpha-D-galactopyranoside

ChemComp-BNG:
nonyl beta-D-glucopyranoside / detergent*YM

Source
  • escherichia coli (strain k12) (bacteria)
KeywordsTRANSPORT PROTEIN / Membrane Protein / Transporter / Alpha-Helical / Major Facilitator Superfamily (MFS)

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