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-Structure paper
Title | Structure-Based Design of Macrocyclic Coagulation Factor VIIa Inhibitors. |
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Journal, issue, pages | J. Med. Chem., Vol. 58, Page 6225-6236, Year 2015 |
Publish date | May 20, 2015 (structure data deposition date) |
Authors | Priestley, E.S. / Cheney, D.L. / DeLucca, I. / Wei, A. / Luettgen, J.M. / Rendina, A.R. / Wong, P.C. / Wexler, R.R. |
External links | J. Med. Chem. / PubMed:26151189 |
Methods | X-ray diffraction |
Resolution | 2.06 - 2.6 Å |
Structure data | PDB-4zxx: PDB-4zxy: |
Chemicals | ChemComp-4T0: ChemComp-CA: ChemComp-SO4: ChemComp-HOH: ChemComp-4T1: ChemComp-GOL: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / GLYCOPROTEIN / HYDROLASE / SERINE PROTEASE / PLASMA / BLOOD COAGULATION FACTOR / PROTEIN INHIBITOR COMPLEX / CALCIUM-BINDING / HYDROLASE-HYDROLASE INHIBITOR complex |