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Structure paper

TitleMolecular basis for the specific recognition of the metazoan cyclic GMP-AMP by the innate immune adaptor protein STING.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 8947-8952, Year 2015
Publish dateMay 29, 2015 (structure data deposition date)
AuthorsShi, H. / Wu, J. / Chen, Z.J. / Chen, C.
External linksProc. Natl. Acad. Sci. USA / PubMed:26150511
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-5bqx:
Crystal structure of human STING in complex with 3'2'-cGAMP
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-4UR:
3'2'-cGAMP

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / STING / 3'2'-cGAMP

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