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TitleStructural Insights Reveal the Dynamics of the Repeating r(CAG) Transcript Found in Huntington's Disease (HD) and Spinocerebellar Ataxias (SCAs)
Journal, issue, pagesPlos One, Vol. 10, Page e0131788-e0131788, Year 2015
Publish dateJul 23, 2014 (structure data deposition date)
AuthorsTawani, A. / Kumar, A.
External linksPlos One / PubMed:26148061
MethodsNMR (solution) / X-ray diffraction
Resolution2.301 Å
Structure data

PDB-2ms5:
Structural dynamics of double-helical RNA having CAG motif
Method: SOLUTION NMR

PDB-4yn6:
Structural Insight reveals dynamics in repeating r(CAG) transcript found in Huntington's disease (HD) and Spinocerebellar ataxias (SCAs)
Method: X-RAY DIFFRACTION / Resolution: 2.301 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • synthetic construct (others)
KeywordsRNA / CAG repeat expansion / Trinucleotide repeats / Huntington's Disease / Trinucleotide repeat / Huntington's disease (HD) / Spinocerebellar ataxias (SCAs)

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