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TitleConversion of cell-survival activity of Akt into apoptotic death of cancer cells by two mutations on the BIM BH3 domain.
Journal, issue, pagesCell Death Dis, Vol. 6, Page e1804-e1804, Year 2015
Publish dateMar 3, 2015 (structure data deposition date)
AuthorsKim, J.S. / Ku, B. / Woo, T.G. / Oh, A.Y. / Jung, Y.S. / Soh, Y.M. / Yeom, J.H. / Lee, K. / Park, B.J. / Oh, B.H. / Ha, N.C.
External linksCell Death Dis / PubMed:26136077
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-4yj4:
Crystal structure of Bcl-xL in complex with the BIM BH3 domain containing Ile155-to-Arg and Glu158-to-phosphoserine mutations
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-ACT:
ACETATE ION

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • homo sapiens (human)
KeywordsAPOPTOSIS / Bcl-xL / BIM / BH3

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