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Structure paper

TitleAnalysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor Receptor.
Journal, issue, pagesMol. Cell. Biol., Vol. 35, Page 3083-3102, Year 2015
Publish dateJul 17, 2015 (structure data deposition date)
AuthorsKovacs, E. / Das, R. / Wang, Q. / Collier, T.S. / Cantor, A. / Huang, Y. / Wong, K. / Mirza, A. / Barros, T. / Grob, P. ...Kovacs, E. / Das, R. / Wang, Q. / Collier, T.S. / Cantor, A. / Huang, Y. / Wong, K. / Mirza, A. / Barros, T. / Grob, P. / Jura, N. / Bose, R. / Kuriyan, J.
External linksMol. Cell. Biol. / PubMed:26124280
MethodsX-ray diffraction
Resolution1.55 - 1.9 Å
Structure data

PDB-5cnn:
Crystal structure of the EGFR kinase domain mutant I682Q
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-5cno:
Crystal structure of the EGFR kinase domain mutant V924R
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

Chemicals

ChemComp-ANP:
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER / AMP-PNP, energy-carrying molecule analogue*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / kinase EGFR

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