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TitleFunctional and Structural Characterization of Human V3-Specific Monoclonal Antibody 2424 with Neutralizing Activity against HIV-1 JRFL.
Journal, issue, pagesJ. Virol., Vol. 89, Page 9090-9102, Year 2015
Publish dateJan 14, 2015 (structure data deposition date)
AuthorsKumar, R. / Pan, R. / Upadhyay, C. / Mayr, L. / Cohen, S. / Wang, X.H. / Balasubramanian, P. / Nadas, A. / Seaman, M.S. / Zolla-Pazner, S. ...Kumar, R. / Pan, R. / Upadhyay, C. / Mayr, L. / Cohen, S. / Wang, X.H. / Balasubramanian, P. / Nadas, A. / Seaman, M.S. / Zolla-Pazner, S. / Gorny, M.K. / Kong, X.P. / Hioe, C.E.
External linksJ. Virol. / PubMed:26109728
MethodsX-ray diffraction
Resolution2.68 - 3.179 Å
Structure data

PDB-4xmk:
Crystal structure of Fab of HIV-1 gp120 V3-specific human monoclonal antibody 2424 in complex with JR-FL V3 peptide
Method: X-RAY DIFFRACTION / Resolution: 3.179 Å

PDB-4xml:
Crystal structure of Fab of HIV-1 gp120 V3-specific human monoclonal antibody 2424
Method: X-RAY DIFFRACTION / Resolution: 2.68 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • human immunodeficiency virus 1
Keywordsimmune system/viral protein / HIV-1 gp120 / monoclonal antibody / immune system-viral protein complex / IMMUNE SYSTEM

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