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TitleStructural Insights Into the Recognition of Cisplatin and Aaf-Dg Lesion by Rad14 (Xpa).
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 8272-, Year 2015
Publish dateMay 28, 2015 (structure data deposition date)
AuthorsKoch, S.C. / Kuper, J. / Gasteiger, K.L. / Simon, N. / Strasser, R. / Eisen, D. / Geiger, S. / Schneider, S. / Kisker, C. / Carell, T.
External linksProc. Natl. Acad. Sci. USA / PubMed:26100901
MethodsX-ray diffraction
Resolution1.8 - 2.8 Å
Structure data

PDB-5a39:
Structure of Rad14 in complex with cisplatin containing DNA
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

PDB-5a3d:
Structural insights into the recognition of cisplatin and AAF-dG lesions by Rad14 (XPA)
Method: X-RAY DIFFRACTION / Resolution: 1.8 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-CPT:
Cisplatin / medication, chemotherapy*YM

ChemComp-HOH:
WATER

Source
  • saccharomyces cerevisiae (brewer's yeast)
  • synthetic construct (others)
KeywordsREPLICATION / DNA REPAIR / DNA DAMAGE RECOGNITION / CISPLATIN / DNA BINDING PROTEIN / XPA / RAD14 / NER / AAF-DG

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