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TitleTwo crystal structures of the FK506-binding domain of Plasmodium falciparum FKBP35 in complex with rapamycin at high resolution
Journal, issue, pagesActa Crystallogr. ,Sect. D, Vol. 71, Page 1319-1327, Year 2015
Publish dateJul 7, 2014 (structure data deposition date)
AuthorsBianchin, A. / Allemand, F. / Bell, A. / Chubb, A.J. / Guichou, J.-F.
External linksActa Crystallogr. ,Sect. D / PubMed:26057671
MethodsX-ray diffraction
Resolution1.4 - 1.44 Å
Structure data

PDB-4qt2:
Crystal Structure of the FK506-Binding Domain of Plasmodium Falciparum FKBP35 in complex with Rapamycin
Method: X-RAY DIFFRACTION / Resolution: 1.44 Å

PDB-4qt3:
Crystal structure resolution of Plasmodium falciparum FK506 binding domain (FKBP35) in complex with Rapamycin at 1.4A resolution
Method: X-RAY DIFFRACTION / Resolution: 1.4 Å

Chemicals

ChemComp-IMD:
IMIDAZOLE

ChemComp-RAP:
RAPAMYCIN IMMUNOSUPPRESSANT DRUG / immunosuppressant, antibiotic*YM

ChemComp-HOH:
WATER

ChemComp-DTV:
(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL

Source
  • plasmodium falciparum 3d7 (eukaryote)
KeywordsISOMERASE / PPiase / enzyme / rapamycin / FKBP35

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