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Structure paper

TitleStructural evidences for a secondary gold binding site in the hydrophobic box of lysozyme.
Journal, issue, pagesBiometals, Vol. 28, Page 745-754, Year 2015
Publish dateApr 21, 2015 (structure data deposition date)
AuthorsFerraro, G. / Massai, L. / Messori, L. / Cinellu, M.A. / Merlino, A.
External linksBiometals / PubMed:26054833
MethodsX-ray diffraction
Resolution1.96 Å
Structure data

PDB-4zfp:
A new crystal structure for the adduct formed in the reaction between AuSac2, a cytotoxic homoleptic gold(I) compound with the saccharinate ligand, and the model protein hen egg white lysozyme
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NO3:
NITRATE ION

ChemComp-AU:
Unknown entry

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsHYDROLASE / gold compounds / gold-based drugs / protein-metallodrug interactions / metallodrugs

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