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Structure paper

TitleAngiomotin binding-induced activation of Merlin/NF2 in the Hippo pathway
Journal, issue, pagesCell Res., Vol. 25, Page 801-817, Year 2015
Publish dateMay 12, 2015 (structure data deposition date)
AuthorsLi, Y. / Zhou, H. / Li, F. / Chan, S.W. / Lin, Z. / Wei, Z. / Yang, Z. / Guo, F. / Lim, C.J. / Xing, W. ...Li, Y. / Zhou, H. / Li, F. / Chan, S.W. / Lin, Z. / Wei, Z. / Yang, Z. / Guo, F. / Lim, C.J. / Xing, W. / Shen, Y. / Hong, W. / Long, J. / Zhang, M.
External linksCell Res. / PubMed:26045165
MethodsX-ray diffraction
Resolution2.3 - 2.7 Å
Structure data

PDB-4zri:
Crystal structure of Merlin-FERM and Lats2
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4zrj:
Structure of Merlin-FERM and CTD
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-4zrk:
Merlin-FERM and Lats1 complex
Method: X-RAY DIFFRACTION / Resolution: 2.316 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
  • mus musculus (house mouse)
KeywordsSIGNALING PROTEIN/TRANSFERASE / Merlin / FERM / Lats2 / SIGNALING PROTEIN-TRANSFERASE complex / SIGNALING PROTEIN / CTD / Lats1

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