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TitleStructural Congruency of Ligand Binding to the Insulin and Insulin/Type 1 Insulin-like Growth Factor Hybrid Receptors.
Journal, issue, pagesStructure, Vol. 23, Page 1271-1282, Year 2015
Publish dateJan 22, 2015 (structure data deposition date)
AuthorsMenting, J.G. / Lawrence, C.F. / Kong, G.K. / Margetts, M.B. / Ward, C.W. / Lawrence, M.C.
External linksStructure / PubMed:26027733
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-4xss:
Insulin-like growth factor I in complex with site 1 of a hybrid insulin receptor / Type 1 insulin-like growth factor receptor
Method: X-RAY DIFFRACTION / Resolution: 3 Å

PDB-4xst:
Structure of the endoglycosidase-H treated L1-CR domains of the human insulin receptor in complex with residues 697-719 of the human insulin receptor (A-isoform)
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

Source
  • homo sapiens (human)
  • rattus norvegicus (Norway rat)
KeywordsHormone/hormone receptor / CELL SURFACE RECEPTOR/IMMUNE SYSTEM / INSULIN RECEPTOR / CT PEPTIDE / INSULIN-LIKE GROWTH FACTOR RECEPTOR / HORMONE RECEPTOR-HORMONE-IMMUNE SYSTEM COMPLEX / Hormone-hormone receptor complex / Insulin micro-receptor

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