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Structure paper

TitleStructural Basis for the Stereochemical Control of Amine Installation in Nucleotide Sugar Aminotransferases.
Journal, issue, pagesAcs Chem. Biol., Vol. 10, Page 2048-2056, Year 2015
Publish dateApr 13, 2015 (structure data deposition date)
AuthorsWang, F. / Singh, S. / Xu, W. / Helmich, K.E. / Miller, M.D. / Cao, H. / Bingman, C.A. / Thorson, J.S. / Phillips, G.N.
External linksAcs Chem. Biol. / PubMed:26023720
MethodsX-ray diffraction
Resolution2.24 Å
Structure data

PDB-4zah:
Crystal structure of sugar aminotransferase WecE with External Aldimine VII from Escherichia coli K-12
Method: X-RAY DIFFRACTION / Resolution: 2.24 Å

Chemicals

ChemComp-T5K:
[[(2R,3S,5R)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(2R,3R,4S,5R,6R)-6-methyl-5-[(E)-[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylideneamino]-3,4-bis(oxidanyl)oxan-2-yl] hydrogen phosphate

ChemComp-HOH:
WATER

Source
  • escherichia coli (strain k12) (bacteria)
KeywordsTRANSFERASE / sugar aminotransferase / Structural Genomics / PSI-Biology / Protein Structure Initiative / Enzyme Discovery for Natural Product Biosynthesis / NatPro

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