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TitleRobust Antibody-Antigen Complexes Prediction Generated by Combining Sequence Analyses, Mutagenesis, In Vitro Evolution, X-ray Crystallography and In Silico Docking.
Journal, issue, pagesJ. Mol. Biol., Vol. 427, Page 2647-2662, Year 2015
Publish dateAug 27, 2014 (structure data deposition date)
AuthorsLoyau, J. / Didelot, G. / Malinge, P. / Ravn, U. / Magistrelli, G. / Depoisier, J.F. / Pontini, G. / Poitevin, Y. / Kosco-Vilbois, M. / Fischer, N. ...Loyau, J. / Didelot, G. / Malinge, P. / Ravn, U. / Magistrelli, G. / Depoisier, J.F. / Pontini, G. / Poitevin, Y. / Kosco-Vilbois, M. / Fischer, N. / Thore, S. / Rousseau, F.
External linksJ. Mol. Biol. / PubMed:26013163
MethodsX-ray diffraction
Resolution2.753 - 3.45 Å
Structure data

PDB-4r7d:
Fab Hu 15C1
Method: X-RAY DIFFRACTION / Resolution: 2.753 Å

PDB-4r7n:
Fab C2E3
Method: X-RAY DIFFRACTION / Resolution: 3.45 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / TLR4 antibody

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