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-Structure paper
Title | Substituted Bis-THF Protease Inhibitors with Improved Potency against Highly Resistant Mature HIV-1 Protease PR20. |
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Journal, issue, pages | J. Med. Chem., Vol. 58, Page 5088-5095, Year 2015 |
Publish date | Feb 23, 2015 (structure data deposition date) |
Authors | Agniswamy, J. / Louis, J.M. / Shen, C.H. / Yashchuk, S. / Ghosh, A.K. / Weber, I.T. |
External links | J. Med. Chem. / PubMed:26010498 |
Methods | X-ray diffraction |
Resolution | 1.3 - 1.35 Å |
Structure data | PDB-4ye3: PDB-4yhq: |
Chemicals | ChemComp-Y1: ChemComp-CL: ChemComp-GOL: ChemComp-G04: ChemComp-HOH: ChemComp-G10: ChemComp-NA: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / HIV-1 Protease / Drug resistance / HYDROLASE-HYDROLASE INHIBITOR complex / HIV Protease / Mutant / Drug resistant / Inhibitor |