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TitleMarine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha 7 from Muscle alpha 12 beta gamma delta nAChRs.
Journal, issue, pagesStructure, Vol. 23, Page 1106-1115, Year 2015
Publish dateJan 5, 2015 (structure data deposition date)
AuthorsBourne, Y. / Sulzenbacher, G. / Radic, Z. / Araoz, R. / Reynaud, M. / Benoit, E. / Zakarian, A. / Servent, D. / Molgo, J. / Taylor, P. / Marchot, P.
External linksStructure / PubMed:26004441
MethodsX-ray diffraction
Resolution1.9 - 2.2 Å
Structure data

PDB-4xhe:
Crystal Structure of A-AChBP in complex with pinnatoxin A
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-4xk9:
Crystal structure of A-AChBP in complex with pinnatoxin G
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-40P:
Pinnatoxin A

ChemComp-CA:
Unknown entry

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

ChemComp-41J:
Pinnatoxin G

Source
  • aplysia californica (California sea hare)
KeywordsACETYLCHOLINE-BINDING PROTEIN / receptor / phycotoxin / pinnatoxin / membrane protein

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