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TitleAntibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms.
Journal, issue, pagesImmunity, Vol. 42, Page 815-825, Year 2015
Publish dateMar 13, 2015 (structure data deposition date)
AuthorsSpangler, J.B. / Tomala, J. / Luca, V.C. / Jude, K.M. / Dong, S. / Ring, A.M. / Votavova, P. / Pepper, M. / Kovar, M. / Garcia, K.C.
External linksImmunity / PubMed:25992858
MethodsX-ray diffraction
Resolution2.194 - 2.826 Å
Structure data

PDB-4yqx:
Mouse IL-2 Bound to JES6-1 scFv Fragment
Method: X-RAY DIFFRACTION / Resolution: 2.826 Å

PDB-4yue:
Mouse IL-2 Bound to S4B6 Fab Fragment
Method: X-RAY DIFFRACTION / Resolution: 2.194 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-GOL:
GLYCEROL

Source
  • rattus norvegicus (Norway rat)
  • mus musculus (house mouse)
KeywordsCYTOKINE/IMMUNE SYSTEM / chemokine / antibody / complex / CYTOKINE-IMMUNE SYSTEM complex

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