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-Structure paper
Title | Structure-Guided Design of Highly Selective and Potent Covalent Inhibitors of Erk1/2. |
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Journal, issue, pages | J. Med. Chem., Vol. 58, Page 4790-, Year 2015 |
Publish date | Apr 10, 2015 (structure data deposition date) |
Authors | Ward, R.A. / Colclough, N. / Challinor, M. / Debreczeni, J. / Eckersley, K. / Fairley, G. / Feron, L. / Flemington, V. / Graham, M.A. / Greenwood, R. ...Ward, R.A. / Colclough, N. / Challinor, M. / Debreczeni, J. / Eckersley, K. / Fairley, G. / Feron, L. / Flemington, V. / Graham, M.A. / Greenwood, R. / Hopcroft, P. / Howard, T.D. / James, M. / Jones, C.D. / Jones, C.R. / Renshaw, J. / Roberts, K. / Snow, L. / Tonge, M. / Yeung, K. |
External links | J. Med. Chem. / PubMed:25977981 |
Methods | X-ray diffraction |
Resolution | 1.33 - 1.89 Å |
Structure data | PDB-4zzm: PDB-4zzn: PDB-4zzo: |
Chemicals | ChemComp-SO4: ChemComp-CQ6: ChemComp-HOH: ChemComp-CQ8: ChemComp-CQ3: |
Source |
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Keywords | TRANSFERASE |