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Structure paper

TitleOxaliplatin vs. cisplatin: competition experiments on their binding to lysozyme.
Journal, issue, pagesDalton Trans, Vol. 44, Page 10392-10398, Year 2015
Publish dateApr 1, 2015 (structure data deposition date)
AuthorsMarasco, D. / Messori, L. / Marzo, T. / Merlino, A.
External linksDalton Trans / PubMed:25974859
MethodsX-ray diffraction
Resolution1.85 - 1.95 Å
Structure data

PDB-4z46:
X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-4zee:
X-ray structure of the bis-platinum lysozyme adduct formed in the reaction between the protein and the two drugs Cisplatin and Oxaliplatin (preparation 2)
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-NO3:
NITRATE ION

ChemComp-NA:
Unknown entry

ChemComp-1PT:
CYCLOHEXANE-1(R),2(R)-DIAMINE-PLATINUM(II) / medication, antineoplastic*YM

ChemComp-CPT:
Cisplatin / medication, chemotherapy*YM

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsHYDROLASE / cisplatin / Oxaliplatin / protein platination / anticancer drugs / ciapltin / platin based drugs / cancer

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