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-Structure paper
Title | Addressing phototoxicity observed in a novel series of biaryl derivatives: Discovery of potent, selective and orally active phosphodiesterase 10A inhibitor ASP9436 |
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Journal, issue, pages | Bioorg. Med. Chem., Vol. 23, Page 3351-3367, Year 2015 |
Publish date | Feb 2, 2015 (structure data deposition date) |
Authors | Hamaguchi, W. / Masuda, N. / Miyamoto, S. / Kikuchi, S. / Narazaki, F. / Shiina, Y. / Seo, R. / Amano, Y. / Mihara, T. / Moriguchi, H. / Hattori, K. |
External links | Bioorg. Med. Chem. / PubMed:25960322 |
Methods | X-ray diffraction |
Resolution | 2.03 Å |
Structure data | PDB-4xy2: |
Chemicals | ChemComp-ZN: ChemComp-MG: ChemComp-490: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE INHIBITOR / Phosphodiesterase / HYDROLASE-HYDROLASE INHIBITOR complex |