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TitleStoichiometry of Heteromeric BAFF and APRIL Cytokines Dictates Their Receptor Binding and Signaling Properties.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 16330-16342, Year 2015
Publish dateApr 16, 2015 (structure data deposition date)
AuthorsSchuepbach-Mallepell, S. / Das, D. / Willen, L. / Vigolo, M. / Tardivel, A. / Lebon, L. / Kowalczyk-Quintas, C. / Nys, J. / Smulski, C. / Zheng, T.S. ...Schuepbach-Mallepell, S. / Das, D. / Willen, L. / Vigolo, M. / Tardivel, A. / Lebon, L. / Kowalczyk-Quintas, C. / Nys, J. / Smulski, C. / Zheng, T.S. / Maskos, K. / Lammens, A. / Jiang, X. / Hess, H. / Tan, S.L. / Schneider, P.
External linksJ. Biol. Chem. / PubMed:25953898
MethodsX-ray diffraction
Resolution2.43 Å
Structure data

PDB-4zch:
Single-chain human APRIL-BAFF-BAFF Heterotrimer
Method: X-RAY DIFFRACTION / Resolution: 2.43 Å

Chemicals

ChemComp-144:
TRIS-HYDROXYMETHYL-METHYL-AMMONIUM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCYTOKINE / B-cell activating factor / A proliferation-inducing ligand / TNF superfamily; cytokine / PROTEROS BIOSTRUCTURES GMBH

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