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TitleStructural Insights into the Neutralization Properties of the Fully Human, Anti-interferon Monoclonal Antibody Sifalimumab.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 14979-14985, Year 2015
Publish dateMar 12, 2015 (structure data deposition date)
AuthorsOganesyan, V. / Peng, L. / Woods, R.M. / Wu, H. / Dall'Acqua, W.F.
External linksJ. Biol. Chem. / PubMed:25925951
MethodsX-ray diffraction
Resolution3 Å
Structure data

PDB-4ypg:
Structural Insights Into the Neutralization Properties of a Human Anti-Interferon Monoclonal Antibody
Method: X-RAY DIFFRACTION / Resolution: 3 Å

Chemicals

ChemComp-NI:
NICKEL (II) ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / therapeutic mAb / IFN-alpha2A

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