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TitleDegree of Recruitment of DOT1L to MLL-AF9 Defines Level of H3K79 Di- and Tri-methylation on Target Genes and Transformation Potential.
Journal, issue, pagesCell Rep, Vol. 11, Page 808-820, Year 2015
Publish dateSep 24, 2014 (structure data deposition date)
AuthorsKuntimaddi, A. / Achille, N.J. / Thorpe, J. / Lokken, A.A. / Singh, R. / Hemenway, C.S. / Adli, M. / Zeleznik-Le, N.J. / Bushweller, J.H.
External linksCell Rep / PubMed:25921540
MethodsNMR (solution)
Structure data

PDB-2mv7:
Solution NMR structure of DOT1L in complex with AF9 (DOT1L-AF9)
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsProtein Binding/Transferase / MIXED LINEAGE LEUKEMIA / LEUKEMIA / Protein Binding-Transferase complex

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