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-Structure paper
Title | Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4. |
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Journal, issue, pages | Angew. Chem. Int. Ed. Engl., Vol. 54, Page 12398-12403, Year 2015 |
Publish date | Nov 27, 2014 (structure data deposition date) |
Authors | Schroder, P. / Forster, T. / Kleine, S. / Becker, C. / Richters, A. / Ziegler, S. / Rauh, D. / Kumar, K. / Waldmann, H. |
External links | Angew. Chem. Int. Ed. Engl. / PubMed:25908259 |
Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | PDB-4rvt: |
Chemicals | ChemComp-3XM: ChemComp-MES: ChemComp-HOH: |
Source |
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Keywords | Transferase/Transferase inhibitor / Pyridin-2(1H)-one Ligand / Type I / DFG-in / Serine/Threonine kinase / Transferase-Transferase inhibitor complex |