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Structure paper

TitleBh3 induced conformational changes in Bcl-Xl revealed by crystal structure and comparative analysis.
Journal, issue, pagesProteins, Vol. 83, Page 1262-1272, Year 2015
Publish dateJul 14, 2014 (structure data deposition date)
AuthorsRajan, S. / Choi, M. / Baek, K. / Yoon, H.S.
External linksProteins / PubMed:25907960
MethodsX-ray diffraction
Resolution1.531 - 2.05 Å
Structure data

PDB-4qve:
Crystal structure of Bcl-xL in complex with BID BH3 domain
Method: X-RAY DIFFRACTION / Resolution: 2.05 Å

PDB-4qvf:
Crystal structure of Bcl-xL in complex with BIM BH3 domain
Method: X-RAY DIFFRACTION / Resolution: 1.531 Å

Chemicals

ChemComp-IMD:
IMIDAZOLE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsAPOPTOSIS / Protein-peptide complex / Bcl-2 like / Heterodimer / Anti-apoptotic / BH3 binding / BID BH3 / BIM BH3

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