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Structure paper

TitleExonuclease TREX1 degrades double-stranded DNA to prevent spontaneous lupus-like inflammatory disease.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 5117-5122, Year 2015
Publish dateMar 10, 2015 (structure data deposition date)
AuthorsGrieves, J.L. / Fye, J.M. / Harvey, S. / Grayson, J.M. / Hollis, T. / Perrino, F.W.
External linksProc. Natl. Acad. Sci. USA / PubMed:25848017
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-4ynq:
TREX1-dsDNA complex
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-TMP:
THYMIDINE-5'-PHOSPHATE

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
  • synthetic construct (others)
KeywordsHydrolase/DNA / protein-DNA complex / exonuclease / trex1 / Hydrolase-DNA complex

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