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Structure paper

TitleA modular toolkit to inhibit proline-rich motif-mediated protein-protein interactions.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 5011-5016, Year 2015
Publish dateSep 27, 2013 (structure data deposition date)
AuthorsOpitz, R. / Muller, M. / Reuter, C. / Barone, M. / Soicke, A. / Roske, Y. / Piotukh, K. / Huy, P. / Beerbaum, M. / Wiesner, B. ...Opitz, R. / Muller, M. / Reuter, C. / Barone, M. / Soicke, A. / Roske, Y. / Piotukh, K. / Huy, P. / Beerbaum, M. / Wiesner, B. / Beyermann, M. / Schmieder, P. / Freund, C. / Volkmer, R. / Oschkinat, H. / Schmalz, H.G. / Kuhne, R.
External linksProc. Natl. Acad. Sci. USA / PubMed:25848013
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-4my6:
EnaH-EVH1 in complex with peptidomimetic low-molecular weight inhibitor Ac-[2-Cl-F]-[ProM-2]-[ProM-1]-OH
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-3VH:
Unknown entry

ChemComp-BR:
BROMIDE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCell adhesion/inhibitor / MOLECULAR RECOGNITION / ACTIN DYNAMICS / Cell adhesion-inhibitor complex

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