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Structure paper

TitleThe crystal structure of DR6 in complex with the amyloid precursor protein provides insight into death receptor activation.
Journal, issue, pagesGenes Dev., Vol. 29, Page 785-790, Year 2015
Publish dateMar 8, 2015 (structure data deposition date)
AuthorsXu, K. / Olsen, O. / Tzvetkova-Robev, D. / Tessier-Lavigne, M. / Nikolov, D.B.
External linksGenes Dev. / PubMed:25838500
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-4yn0:
Crystal structure of APP E2 domain in complex with DR6 CRD domain
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • mus musculus (house mouse)
KeywordsApoptosis/Cell Adhesion / Alzheimer / Neuron pruning / Amyloid precursor protein / Apoptosis-Cell Adhesion complex

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