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-Structure paper
Title | Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 112, Page 4666-4671, Year 2015 |
Publish date | Sep 12, 2014 (structure data deposition date) |
Authors | Hayashi, Y. / Caboni, L. / Das, D. / Yumoto, F. / Clayton, T. / Deller, M.C. / Nguyen, P. / Farr, C.L. / Chiu, H.J. / Miller, M.D. ...Hayashi, Y. / Caboni, L. / Das, D. / Yumoto, F. / Clayton, T. / Deller, M.C. / Nguyen, P. / Farr, C.L. / Chiu, H.J. / Miller, M.D. / Elsliger, M.A. / Deacon, A.M. / Godzik, A. / Lesley, S.A. / Tomoda, K. / Conklin, B.R. / Wilson, I.A. / Yamanaka, S. / Fletterick, R.J. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:25825768 |
Methods | X-ray diffraction |
Resolution | 3.3 Å |
Structure data | PDB-4rbo: |
Source |
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Keywords | DNA BINDING PROTEIN / TRANSCRIPTION/DNA / Homeobox / PF00046 family / Structural Genomics / Joint Center for Structural Genomics / JCSG / Partnership for Stem Cell Biology / STEMCELL / Protein Structure Initiative / PSI-BIOLOGY / TRANSCRIPTION / TRANSCRIPTION-DNA complex |