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TitleCysteine Specific Targeting of the Functionally Distinct Peroxiredoxin and Glutaredoxin Proteins by the Investigational Disulfide BNP7787.
Journal, issue, pagesMolecules, Vol. 20, Page 4928-4950, Year 2015
Publish dateNov 4, 2014 (structure data deposition date)
AuthorsParker, A.R. / Petluru, P.N. / Nienaber, V.L. / Badger, J. / Leverett, B.D. / Jair, K. / Sridhar, V. / Logan, C. / Ayala, P.Y. / Kochat, H. / Hausheer, F.H.
External linksMolecules / PubMed:25793542
MethodsX-ray diffraction
Resolution1.08 - 2.256 Å
Structure data

PDB-4rqr:
Crystal Structure of Human Glutaredoxin with MESNA
Method: X-RAY DIFFRACTION / Resolution: 1.08 Å

PDB-4rqx:
Crystal structure of human peroxiredoxin 4(THIOREDOXIN PEROXIDASE) with MESNA
Method: X-RAY DIFFRACTION / Resolution: 2.256 Å

Chemicals

ChemComp-COM:
1-THIOETHANESULFONIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsELECTRON TRANSPORT / REDOX-ACTIVE CENTER / OXIDOREDUCTASE / PEROXIREDOXIN / THIOREDOXIN

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