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-Structure paper
Title | Engineered stabilization and structural analysis of the autoinhibited conformation of PDE4. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 112, Page E1414-E1422, Year 2015 |
Publish date | Nov 19, 2014 (structure data deposition date) |
Authors | Cedervall, P. / Aulabaugh, A. / Geoghegan, K.F. / McLellan, T.J. / Pandit, J. |
External links | Proc. Natl. Acad. Sci. USA / PubMed:25775568 |
Methods | X-ray diffraction |
Resolution | 2.58 - 3.22 Å |
Structure data | PDB-4wzi: PDB-4x0f: |
Chemicals | ChemComp-ZN: ChemComp-NA: ChemComp-MG: ChemComp-IOD: ChemComp-HOH: ChemComp-ROL: |
Source |
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Keywords | HYDROLASE / Phosphodiesterase / hydrolase/hydrolase inhibitor / inhibitor / complex / hydrolase-hydrolase inhibitor complex |