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Structure paper

TitleStructural characterization of an alternative mode of tigecycline binding to the bacterial ribosome.
Journal, issue, pagesAntimicrob. Agents Chemother., Vol. 59, Page 2849-2854, Year 2015
Publish dateFeb 27, 2015 (structure data deposition date)
AuthorsSchedlbauer, A. / Kaminishi, T. / Ochoa-Lizarralde, B. / Dhimole, N. / Zhou, S. / Lopez-Alonso, J.P. / Connell, S.R. / Fucini, P.
External linksAntimicrob. Agents Chemother. / PubMed:25753625
MethodsX-ray diffraction
Resolution3.417 Å
Structure data

PDB-4yhh:
Crystal structure of the 30S ribosomal subunit from Thermus thermophilus in complex with tigecycline
Method: X-RAY DIFFRACTION / Resolution: 3.417 Å

Chemicals

ChemComp-T1C:
TIGECYCLINE / medication, antibiotic*YM

ChemComp-MG:
Unknown entry

ChemComp-ZN:
Unknown entry

Source
  • thermus thermophilus hb8 (bacteria)
KeywordsRIBOSOME / protein synthesis / antibiotic

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