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-Structure paper
Title | Crystal structures of immunoglobulin Fc heterodimers reveal the molecular basis for heterodimer formation. |
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Journal, issue, pages | Mol. Immunol., Vol. 65, Page 377-383, Year 2015 |
Publish date | Dec 11, 2014 (structure data deposition date) |
Authors | Choi, H.J. / Seok, S.H. / Kim, Y.J. / Seo, M.D. / Kim, Y.S. |
External links | Mol. Immunol. / PubMed:25743157 |
Methods | X-ray diffraction |
Resolution | 2.498 - 2.499 Å |
Structure data | PDB-4x98: PDB-4x99: |
Chemicals | ChemComp-HOH: |
Source |
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Keywords | IMMUNE SYSTEM / bispecific antibody / immunoglobulin Fc heterodimer / CH3 domain interface / asymmetric disulfide bonds / thermal stability / Fc engineering |