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Structure paper

TitleStructural basis for penetration of the glycan shield of hepatitis C virus e2 glycoprotein by a broadly neutralizing human antibody.
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 10117-10125, Year 2015
Publish dateJan 27, 2015 (structure data deposition date)
AuthorsLi, Y. / Pierce, B.G. / Wang, Q. / Keck, Z.Y. / Fuerst, T.R. / Foung, S.K. / Mariuzza, R.A.
External linksJ. Biol. Chem. / PubMed:25737449
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-4xvj:
STRUCTURE OF THE HEPATITIS C VIRUS ENVELOPE GLYCOPROTEIN E2 ANTIGENIC 2 REGION 412-423 BOUND TO THE BROADLY NEUTRALIZING ANTIBODY HC33.1
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • hepatitis c virus
KeywordsIMMUNE SYSTEM / Antibody-antigen complex

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