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Structure paper

TitleCleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page 3344-3349, Year 2015
Publish dateFeb 13, 2015 (structure data deposition date)
AuthorsDang, S. / Wu, S. / Wang, J. / Li, H. / Huang, M. / He, W. / Li, Y.M. / Wong, C.C. / Shi, Y.
External linksProc. Natl. Acad. Sci. USA / PubMed:25733893
MethodsX-ray diffraction
Resolution3.855 Å
Structure data

PDB-4y6k:
Complex structure of presenilin homologue PSH bound to an inhibitor
Method: X-RAY DIFFRACTION / Resolution: 3.855 Å

Chemicals

ChemComp-4B5:
N-{(2R,4S,5S)-2-benzyl-5-[(tert-butoxycarbonyl)amino]-4-hydroxy-6-phenylhexanoyl}-L-leucyl-L-phenylalaninamide

Source
  • methanoculleus marisnigri jr1 (archaea)
KeywordsMEMBRANE PROTEIN/INHIBITOR / Complex / Inhibitor / MEMBRANE PROTEIN-INHIBITOR complex

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