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TitleSynthesis of Dimeric Adp-Ribose and its Structure with Human Poly(Adp-Ribose) Glycohydrolase.
Journal, issue, pagesJ. Am. Chem. Soc., Vol. 137, Page 3558-, Year 2015
Publish dateJul 9, 2015 (structure data deposition date)
AuthorsLambrecht, M.J. / Brichacek, M. / Barkauskaite, E. / Ariza, A. / Ahel, I. / Hergenrother, P.J.
External linksJ. Am. Chem. Soc. / PubMed:25706250
MethodsX-ray diffraction
Resolution1.95 Å
Structure data

PDB-5a7r:
Human poly(ADP-ribose) glycohydrolase in complex with synthetic dimeric ADP-ribose
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-AR6:
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-SO4:
SULFATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-PPI:
PROPANOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / PARG / ADP-RIBOSE

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