| タイトル | Transition states. Trapping a transition state in a computationally designed protein bottle. |
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| ジャーナル・号・ページ | Science, Vol. 347, Page 863-867, Year 2015 |
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| 掲載日 | 2014年12月30日 (構造データの登録日) |
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著者 | Pearson, A.D. / Mills, J.H. / Song, Y. / Nasertorabi, F. / Han, G.W. / Baker, D. / Stevens, R.C. / Schultz, P.G. |
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リンク | Science / PubMed:25700516 |
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| 手法 | X線回折 |
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| 解像度 | 1.95 - 2.5 Å |
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| 構造データ | PDB-4s02: Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, F42W, Y79A, and F123Y mutant 手法: X-RAY DIFFRACTION / 解像度: 1.95 Å PDB-4s03: Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, Y79I, and F123A mutant 手法: X-RAY DIFFRACTION / 解像度: 2.05 Å PDB-4s0i: Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: 11BIF, 42F, 79S, and 123A mutant 手法: X-RAY DIFFRACTION / 解像度: 2.36 Å PDB-4s0j: Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: 11BIF, 42F, 79S, and 123V mutant 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-4s0k: Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: 11BIF, 42F, 79V, and 123A mutant 手法: X-RAY DIFFRACTION / 解像度: 2.1 Å PDB-4s0l: Biphenylalanine modified threonyl-tRNA synthetase from Pyrococcus abyssi: I11BIF, Y79V, and F123V mutant 手法: X-RAY DIFFRACTION / 解像度: 2.5 Å |
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| 化合物 | |
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| 由来 |  pyrococcus abyssi ge5 (古細菌)
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キーワード | LIGASE / beta-alpha-beta fold / editing domain / tRNA-synthetase / Biphenylalanine and unnatural amino acid / threonine-tRNA ligase / Biphenylalanine / unnatural amino acid |
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