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TitlePeptide Library Approach to Uncover Phosphomimetic Inhibitors of the BRCA1 C-Terminal Domain.
Journal, issue, pagesAcs Chem. Biol., Vol. 10, Page 1198-1208, Year 2015
Publish dateJan 14, 2014 (structure data deposition date)
AuthorsWhite, E.R. / Sun, L. / Ma, Z. / Beckta, J.M. / Danzig, B.A. / Hacker, D.E. / Huie, M. / Williams, D.C. / Edwards, R.A. / Valerie, K. ...White, E.R. / Sun, L. / Ma, Z. / Beckta, J.M. / Danzig, B.A. / Hacker, D.E. / Huie, M. / Williams, D.C. / Edwards, R.A. / Valerie, K. / Glover, J.N. / Hartman, M.C.
External linksAcs Chem. Biol. / PubMed:25654734
MethodsX-ray diffraction
Resolution3.05 Å
Structure data

PDB-4ofb:
Crystal structure of human BRCA1 BRCT in complex with nonphosphopeptide inhibitor
Method: X-RAY DIFFRACTION / Resolution: 3.05 Å

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / BRCT domain / DSB DNA damage repair / non-phosphorylated peptide

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