+Search query
-Structure paper
Title | Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation. |
---|---|
Journal, issue, pages | Nat. Chem. Biol., Vol. 11, Page 189-191, Year 2015 |
Publish date | Dec 10, 2014 (structure data deposition date) |
![]() | Lewis, H.D. / Liddle, J. / Coote, J.E. / Atkinson, S.J. / Barker, M.D. / Bax, B.D. / Bicker, K.L. / Bingham, R.P. / Campbell, M. / Chen, Y.H. ...Lewis, H.D. / Liddle, J. / Coote, J.E. / Atkinson, S.J. / Barker, M.D. / Bax, B.D. / Bicker, K.L. / Bingham, R.P. / Campbell, M. / Chen, Y.H. / Chung, C.W. / Craggs, P.D. / Davis, R.P. / Eberhard, D. / Joberty, G. / Lind, K.E. / Locke, K. / Maller, C. / Martinod, K. / Patten, C. / Polyakova, O. / Rise, C.E. / Rudiger, M. / Sheppard, R.J. / Slade, D.J. / Thomas, P. / Thorpe, J. / Yao, G. / Drewes, G. / Wagner, D.D. / Thompson, P.R. / Prinjha, R.K. / Wilson, D.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 3.1 - 3.29 Å |
Structure data | ![]() PDB-4x8c: ![]() PDB-4x8g: |
Chemicals | ![]() ChemComp-CA: ![]() ChemComp-3YZ: ![]() ChemComp-HOH: ![]() ChemComp-3Z0: |
Source |
|
![]() | Hydrolase/Hydrolase Inhibitor / Hydrolase-Hydrolase Inhibitor complex |