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Structure paper

TitleStructural basis of new allosteric inhibition in Kinesin spindle protein eg5
Journal, issue, pagesAcs Chem. Biol., Vol. 10, Page 1128-1136, Year 2015
Publish dateJan 14, 2014 (structure data deposition date)
AuthorsYokoyama, H. / Sawada, J. / Katoh, S. / Matsuno, K. / Ogo, N. / Ishikawa, Y. / Hashimoto, H. / Fujii, S. / Asai, A.
External linksAcs Chem. Biol. / PubMed:25622007
MethodsX-ray diffraction
Resolution2.8 Å
Structure data

PDB-3wpn:
Kinesin spindle protein Eg5 in complex with ATP-competitive inhibitor PVZB1194
Method: X-RAY DIFFRACTION / Resolution: 2.8 Å

Chemicals

ChemComp-B4S:
3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsCELL CYCLE / motor domain / ATP binding

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