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TitleBiocontainment of genetically modified organisms by synthetic protein design.
Journal, issue, pagesNature, Vol. 518, Page 55-60, Year 2015
Publish dateFeb 16, 2014 (structure data deposition date)
AuthorsMandell, D.J. / Lajoie, M.J. / Mee, M.T. / Takeuchi, R. / Kuznetsov, G. / Norville, J.E. / Gregg, C.J. / Stoddard, B.L. / Church, G.M.
External linksNature / PubMed:25607366
MethodsX-ray diffraction
Resolution2.65 Å
Structure data

PDB-4oud:
Engineered tyrosyl-tRNA synthetase with the nonstandard amino acid L-4,4-biphenylalanine
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

Chemicals

ChemComp-TYR:
TYROSINE

ChemComp-HOH:
WATER

Source
  • escherichia coli (E. coli)
KeywordsLIGASE / complex with L-tyrosine / Rossmann fold / tRNA

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