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Structure paper

TitleMolecular basis for antagonistic activity of anifrolumab, an anti-interferon-alpha receptor 1 antibody.
Journal, issue, pagesMAbs, Vol. 7, Page 428-439, Year 2015
Publish dateJul 20, 2014 (structure data deposition date)
AuthorsPeng, L. / Oganesyan, V. / Wu, H. / Dall'Acqua, W.F. / Damschroder, M.M.
External linksMAbs / PubMed:25606664
MethodsX-ray diffraction
Resolution2.3 Å
Structure data

PDB-4qxg:
Antigen binding fragment of an anti IFNAR1 antibody
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

Chemicals

ChemComp-K:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / IgV and IgC type folds / antigen binding / IFNAR1 / interferon alpha receptor 1

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