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TitleMechanism of RNA polymerase II bypass of oxidative cyclopurine DNA lesions.
Journal, issue, pagesProc. Natl. Acad. Sci. USA, Vol. 112, Page E410-E419, Year 2015
Publish dateDec 7, 2014 (structure data deposition date)
AuthorsWalmacq, C. / Wang, L. / Chong, J. / Scibelli, K. / Lubkowska, L. / Gnatt, A. / Brooks, P.J. / Wang, D. / Kashlev, M.
External linksProc. Natl. Acad. Sci. USA / PubMed:25605892
MethodsX-ray diffraction
Resolution3.96 - 4.1 Å
Structure data

PDB-4x67:
Crystal structure of elongating yeast RNA polymerase II stalled at oxidative Cyclopurine DNA lesions.
Method: X-RAY DIFFRACTION / Resolution: 4.1 Å

PDB-4x6a:
Crystal structure of yeast RNA polymerase II encountering oxidative Cyclopurine DNA lesions
Method: X-RAY DIFFRACTION / Resolution: 3.96 Å

Chemicals

ChemComp-ZN:
Unknown entry

Source
  • saccharomyces cerevisiae (strain atcc 204508 / s288c) (yeast)
  • synthetic construct (others)
KeywordsTRANSCRIPTION/DNA / pol II elongation complex oxidative Cyclopurine DNA lesions / TRANSCRIPTION-DNA complex

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