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TitleMetabolic Fate of Unsaturated Glucuronic/Iduronic Acids from Glycosaminoglycans: MOLECULAR IDENTIFICATION AND STRUCTURE DETERMINATION OF STREPTOCOCCAL ISOMERASE AND DEHYDROGENASE
Journal, issue, pagesJ. Biol. Chem., Vol. 290, Page 6281-6292, Year 2015
Publish dateAug 3, 2014 (structure data deposition date)
AuthorsMaruyama, Y. / Oiki, S. / Takase, R. / Mikami, B. / Murata, K. / Hashimoto, W.
External linksJ. Biol. Chem. / PubMed:25605731
MethodsX-ray diffraction
Resolution1.55 - 2.9 Å
Structure data

PDB-4u8e:
Crystal structure of 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase from Streptococcus agalactiae
Method: X-RAY DIFFRACTION / Resolution: 2 Å

PDB-4u8f:
Crystal structure of 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase complexed with a tartrate
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-4u8g:
Crystal structure of 2-keto-3-deoxy-D-gluconate dehydrogenase from Streptococcus agalactiae
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-TLA:
L(+)-TARTARIC ACID

Source
  • streptococcus agalactiae nem316 (bacteria)
KeywordsISOMERASE / glycosaminoglycan metabolism / rossman fold / 4-deoxy-L-threo-5-hexosulose-uronate / OXIDOREDUCTASE / dehydrogenase / SDR family / rosman fold / NADH

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