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Structure paper

TitleMolecular Determinants for Nuclear Import of Influenza A PB2 by Importin alpha Isoforms 3 and 7.
Journal, issue, pagesStructure, Vol. 23, Page 374-384, Year 2015
Publish dateAug 8, 2014 (structure data deposition date)
AuthorsPumroy, R.A. / Ke, S. / Hart, D.J. / Zachariae, U. / Cingolani, G.
External linksStructure / PubMed:25599645
MethodsX-ray diffraction
Resolution1.698 - 2.7 Å
Structure data

PDB-4uad:
Importin alpha 7 delta IBB in complex with Influenza PB2 Nuclear Localization Domain
Method: X-RAY DIFFRACTION / Resolution: 2.42 Å

PDB-4uae:
Importin alpha 3 delta IBB in complex with Influenza PB2 Nuclear Localization Domain
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-4uaf:
Importin alpha 1 delta IBB in complex with Influenza PB2 nuclear localization domain
Method: X-RAY DIFFRACTION / Resolution: 1.698 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-SO4:
SULFATE ION

ChemComp-PO4:
PHOSPHATE ION

Source
  • homo sapiens (human)
  • influenza a virus
  • mus musculus (house mouse)
KeywordsPROTEIN TRANSPORT / importin karyopherin complex NLS / PROTEIN BINDING

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