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TitlePeroxide-mediated oxidation and inhibition of the peptidyl-prolyl isomerase Pin1.
Journal, issue, pagesBiochim. Biophys. Acta, Vol. 1852, Page 905-912, Year 2015
Publish dateMay 30, 2014 (structure data deposition date)
AuthorsInnes, B.T. / Sowole, M.A. / Gyenis, L. / Dubinsky, M. / Konermann, L. / Litchfield, D.W. / Brandl, C.J. / Shilton, B.H.
External linksBiochim. Biophys. Acta / PubMed:25595659
MethodsX-ray diffraction
Resolution1.865 Å
Structure data

PDB-4qib:
Oxidation-Mediated Inhibition of the Peptidyl-Prolyl Isomerase Pin1
Method: X-RAY DIFFRACTION / Resolution: 1.865 Å

Chemicals

ChemComp-PE4:
2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL / precipitant*YM

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / cis-trans isomerization / Oxidation of active site cysteine / cysteine sulfenic-sulfinic acid redox regulation / parvulin

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